Since their introduction into peptide chemistry by means of Bruce Merrifield in the early 1960 (1) resin beads of a variety of different marks shapes and sizes have been used in a diverse range of chemistry based synthesis applications.

Since their introduction into peptide chemistry by means of Bruce Merrifield in the early 1960 (1) resin beads of a variety of different marks shapes and sizes have been used in a diverse range of chemistry based synthesis applications. athwart the past decade, this has been almost exclusively for the synthesis of recent pharmaceuticals agents, using a mixture of technologies that are now collectively limited combinatorial chemistry. (2)

Beads, however, have multiple uses beyond unsullied synthesis and here, we will discuss their use as sensing devices for a range of chemical transformations,

One issue that has always arisen with regard to solid-phase

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